To assess bone healing, serum level of vitamin D and associated factors at early phase of bone healing.
An institution based prospective follow up study was conducted at University of Gondar teaching hospital, from March to May 2015 among 118 adults who have a new fracture. Blood sample and X-ray result were collected to assess serum vitamin D level and level of bone healing respectively. Data was entered in to Epi- Info version 3.5.4 and exported to SPSS version 20 for analysis. Binary logistic regression with 95% confidence intervals was carried out to identify predictors of outcome variables.
Among the 118 participants 87.3% were males and with the mean age (+SD) of 36.87, +13.4. There was a marginal difference (p<0.053) in the serum vitamin-D level between measurements of the baseline and after a month of fracture. After a month, bone ossification was occurred in 36.4%. Participants who drink milk and milk products after fracture were inversely associated with decrease in serum vitamin-D (AOR = 0.20; 95%CI: 0.05, 0.90). While individual having low dietary diversity score (AOR = 29.1; 95% CI 2.27, 371.65), and ossified bone (AOR = 4.10; 95% CI 1.12, 14.95) were significant associated with decrease in serum vitamin-D. Lower Limp type of fracture (AOR = 0.13; 95%CI0.03, 0.50) was inversely associated with bone healing, While increased dietary diversity score (AOR =18.61; 95%CI 4.10, 84.34) and individuals having a wealth status of high (AOR = 8.61; 95%CI; 1.51, 49.05) were significantly associated with bone healing
The serum vitamin-D level change from the initial measurement after one month following fracture was decreased and this change was highly associated with using milk and milk products, bone healing condition and dietary diversity score. Bone healing was also significantly associated with type of fracture, using milk and milk products, and high wealth status.