Multiple micronutrients in powder through primary healthcare reduce iron deficiency, vitamin A deficiency and improve nutritional status in young Brazilian Amazonian children: a pragmatic controlled trial

Abstract Number Theme Presentation Type Cover Approved
0511 Efficacy or effectiveness of micronutrient interventions Poster Not Approved


Abstract Content


We evaluated the effect of home fortification with multiple micronutrient powders (MNP) on anaemia, growth and micronutrient status of young Amazonian children.


A pragmatic controlled trial was performed with a total of 240 children aged < 2 years. At study baseline, a control group (CG) of children 11 to 14 months was recruited in the routine healthcare for assessing anaemia, anthropometric and micronutrient status. Simultaneously, an intervention group (IG) of infants aged 6-8 mo was recruited in the same health centres to receive MNP daily in complementary feeding for over 2 months. Four to six months after enrolment, the two study groups were compared when the IG participants (n=112) had reached the age of the CG participants (n = 128), at Primary health centres in the city of Rio Branco, Brazilian Amazon.


In the CG, the prevalence of anaemia [haemoglobin (Hb) < 110 g/L], iron deficiency (ID, plasma ferritin < 12 µg/L or soluble transferrin receptor > 8.3 mg/L) and vitamin A deficiency (VAD, serum retinol < 0.70µmol/L) in CG were 20.31%, 72.44% and 18.55%, respectively. Six months after enrolment, in the IG (aged 11-14 months), the prevalence of anaemia, ID and VAD in IG were 15.18%, 25.23% and 4.67%, respectively. The IG had a lower likelihood of ID [PR (95% CI): 0.34 (0.24; 0.49)] and VAD; 0.25 (0.09, 0.64)].


Home fortification of complementary feeding delivered through primary healthcare was effective in reducing iron and vitamin A deficiencies among young Amazonian children.

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