The relationship between obesity, inflammation markers, micronutrients and insulin resistance in school age child

Abstract Number Theme Presentation Type Cover Approved
0480 Prevalence and risk factors for micronutrient status(deficiency, overload) Poster Approved


Abstract Content


The aims of this study was detect prevalence of dyslipidemias, insulin resistance (HOMA –IR) and micronutrients deficiencies and to investigate the relationship between corporal adiposity and inflammation markers, micronutrients and insulin resistance in healthy school age children


Cross-sectional study, 300 children aged 6 – 11 years were included for analysis (139 male and 161 female). Eutrophic, apparently healthy were recruited from two semirural comunities, Santa Cruz and Santa María Begoña, in the state of Querétaro in México during 2012 – 2014. Anthropometric evaluation (weight, height and waist circumference), adiposity (body mass index (IMC), total and abdominal fat), biochemical parameters (glucose, total cholesterol, high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL) and triglycerides), inflammatory markers (C reactive protein (CRP), interleukin 6 (IL-6) and tumor necrosis factor a (TNF-a)), hormones (leptin and insulin) and micronutrients (vitamins A, C, D, E, B12 and folato; minerals Zn and Fe) were analyzed. Mean differences were calculated and multiple regression models were made.


The population under study showed 29.9 % hypertriglyceridemia, 17.2 % low HDL (< 40 mg/dL) and 17.7 % insulin resistance prevalence; also, was observed deficiencies of 19.9% vitamin D and 15.2 % Zn prevalence. Anthropometric, composition corporal, biochemical variables (except glucose and HDL), hormones and inflammatory markers were lower in children with normal IMC and increasing with respect IMC (p < 0.05). Vitamins and minerals were not observed differences in concentration respect to IMC.


Obese children had dyslipidemias and inflammation markers associated to insulin resistance.

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