Vitamin A and E are associated with markers of obesity, inflammation and insulin resistence in Mexican school-aged children.

Abstract Number Theme Presentation Type Cover Approved
0449 Micronutrients, overweight and obesity Poster Approved


Abstract Content


The aim of this study was to determine the relationship between levels of vitamin A, E and D with markers of obesity, insulin resistance and inflammation in school-aged children.


300 children (101.08±18.47 mo) from rural area in Mexico participated in a cross-sectional study. Weight, height, waist circumference and body composition (by DXA) were determined. A fasting blood sample was taken to determine the concentrations of vitamin A, E and D, glucose, insulin, lipid profile, leptin, CRP, TNF-a, IL-6 and IL-10. Logistic regression models were used to analyze associations between variables.


The combined prevalence of overweight/obesity was 28.9%, 18% had insulin resistance, 30% high triglycerides and 17% had low HDL concentrations. Vitamin A was positively associated and vitamin E:lipid ratio was negatively associated with BMI for age, body fat and waist/height ratio (p<0.001). Vitamin A was associated with a higher risk of having elevated leptin levels (OR 1.13, CI 95% 1.07, 1.19, p= 0.000). The risk of lower levels of CRP, IL-6, leptin and insulin resistance was reduced significantly in children with a higher vitamin E:lipid ratio (OR 0.55, 95% CI 0.33, 0.92 p= 0.023; OR 0.44, 95% CI 0.32, 0.73 p= 0.001; OR 0.55, 95% CI 0.36, 0.84 p= 0.006; OR 0.53, 95% CI 0.32, 0.87, p= 0.013). No association was found between vitamin D and the variables studied


Vitamin A was positively associated and vitamin E:lipid ratio was negatively associated with markers of obesity and inflammation in school-aged children living in rural Mexico.

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